Which Is Better Aspirin Or Clopidogrel?

Can I take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST..

Does clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Does clopidogrel affect blood sugar?

The mechanism of glucose lowering activity of clopidogrel is not clear but it could be explained on the basis of clopidogrel inhibitory effect on TNF-α production and this might cause improvement in insulin sensitivity, increase in glucose utilization by peripheral tissue and suppressed hepatic glucose production.

Can I substitute aspirin for clopidogrel?

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.

Why is aspirin and clopidogrel used together?

The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone, according to results of the POINT study.

Are aspirin and clopidogrel the same?

Plavix (clopidogrel) quick comparison of differences. Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).

Can I drink coffee with Plavix?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

What foods should I avoid when taking clopidogrel?

There’s a risk that you could get a stomach ulcer. Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the blood-thinning effect of your medicine.

Which effect is produced on administration of aspirin with clopidogrel?

Aspirin and clopidogrel exert their antiplatelet effects by inhibiting thromboxane A2 production and adenosine diphosphate–induced platelet aggregation pathways, respectively. Aspirin has proven benefits in primary and secondary prevention of coronary artery disease.

How do you know if clopidogrel is working?

You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working. However, if bleeding is excessive, prolonged, or you notice blood in your urine or stool, seek urgent medical advice.

Is it safe to take clopidogrel long term?

Safety Announcement [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

What is the best antiplatelet drug?

Ischaemic stroke and transient ischaemic attack Clopidogrel (75 mg daily) is the preferred antiplatelet. If intolerant of clopidogrel, aspirin in combination with modified-release dipyridamole (200 mg twice a day).

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Is it better to take clopidogrel in the morning or at night?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

When should you not take clopidogrel?

If you have certain health conditions such as a peptic ulcer or bleeding disorder you should not take clopidogrel, unless advised by a specialist. You should use clopidogrel with caution if you have liver or kidney problems. Clopidogrel must not be given to anyone under 16 years old, unless under specialist advice.

What is a natural alternative to Plavix?

Some foods and other substances that may act as natural blood thinners and help reduce the risk of clots include the following list:Turmeric. Share on Pinterest. … Ginger. Share on Pinterest. … Cayenne peppers. Share on Pinterest. … Vitamin E. Share on Pinterest. … Garlic. … Cassia cinnamon. … Ginkgo biloba. … Grape seed extract.More items…

How long should you take clopidogrel?

The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months. I know, it seems long.

How does aspirin and clopidogrel work?

It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots.

Can clopidogrel cause leg pain?

You may have muscle pain while you’re taking Plavix. It’s not known for sure why this occurs in people taking the drug. If you have severe muscle pain while you’re taking Plavix, call your doctor right away. They can check to see what’s causing your discomfort, and they’ll recommend whether you need medical treatment.