What Should You Not Take With Clopidogrel?

What antacids can be taken with clopidogrel?

– Patients who use clopidogrel and need a medication to reduce stomach acid can use antacids and most H2 blockers such as Zantac (ranitidine), Pepcid (famotidine), Axid (nizatidine), but not Tagamet and Tagamet HB (cimetidine)..

Is it safe to take clopidogrel long term?

Safety Announcement [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

Can blood thinners cause acid reflux?

Since blood thinners like Plavix can cause stomach problems including heartburn and ulcers, doctors also used to regularly give patients heartburn drugs.

How long should Clopidogrel be taken?

The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months. I know, it seems long.

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

Does clopidogrel affect blood sugar?

The mechanism of glucose lowering activity of clopidogrel is not clear but it could be explained on the basis of clopidogrel inhibitory effect on TNF-α production and this might cause improvement in insulin sensitivity, increase in glucose utilization by peripheral tissue and suppressed hepatic glucose production.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Should clopidogrel be taken in the morning or evening?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Which is better aspirin or clopidogrel?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).

How do you know if clopidogrel is working?

You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working. However, if bleeding is excessive, prolonged, or you notice blood in your urine or stool, seek urgent medical advice.

What can you not take with clopidogrel?

Clopidogrel may interact with other medicationsDiabetes drug. In most cases, repaglinide should not be taken with clopidogrel. … Stomach acid drugs (proton pump inhibitors) … Nonsteroidal anti-inflammatory drugs (NSAIDs) … Blood thinners.Drugs used to treat depression. … Salicylates (aspirin) … Opioids.

What time of day should I take clopidogrel?

Clopidogrel comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take clopidogrel at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

What drugs interact with clopidogrel?

Serious InteractionsSELECTED PLATELET AGGREGATION INHIBITORS/NSAIDS.CLOPIDOGREL/ESOMEPRAZOLE; OMEPRAZOLE; CIMETIDINE.CLOPIDOGREL/FLUCONAZOLE; KETOCONAZOLE; VORICONAZOLE.CLOPIDOGREL/ETRAVIRINE.CLOPIDOGREL/FELBAMATE.CLOPIDOGREL/TICLOPIDINE.CLOPIDOGREL/FLUOXETINE; FLUVOXAMINE.More items…

Can I drink coffee with clopidogrel?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Is it safe to take omeprazole with clopidogrel?

Concomitant use of clopidogrel and omeprazole or esomeprazole is to be discouraged unless considered essential. Doctors should check whether patients who are taking clopidogrel are also buying over-the-counter omeprazole and consider whether other gastrointestinal therapies would be more suitable.

Does clopidogrel cause stomach problems?

Easy bleeding/bruising, stomach upset/pain, diarrhea, and constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Although unlikely, serious bleeding in the stomach, gut, eyes, or brain may occur.

Which medicines should not be taken together?

5 Over-the-Counter Medicines You Should Never Take TogetherDangerous duo: Tylenol and multi-symptom cold medicines. … Dangerous duo: Any combo of ibuprofen, naproxen, and aspirin. … Dangerous duo: Antihistamines and motion-sickness medications. … Dangerous duo: Anti-diarrheal medicine and calcium supplements. … Dangerous duo: St.