Quick Answer: Why Is Ranitidine Being Recalled?

What is the problem with ranitidine?

NDMA is a probable human carcinogen (a substance that could cause cancer).

In the summer of 2019, the FDA became aware of independent laboratory testing that found NDMA in ranitidine.

Low levels of NDMA are commonly ingested in the diet, for example NDMA is present in foods and in water..

Is ranitidine safe for kidneys?

Ranitidine can damage kidneys because it contains a chemical called NDMA (N-Nitrosodimethylamine), which can cause kidney cancer and reduced kidney function.

Is ranitidine banned in India?

Claiming that Ranitidine has not been banned, T. R. Raghu, Professor of Cardiology at Jayadeva Institute, said none of the key pharmaceutical regulators such as the US FDA, the Drug Controller General of India (DCGI) /CDSCO have asked for a ban. “The recall by a few manufacturers in India was purely voluntary.

How much ranitidine is safe to take?

The usual dose to treat: indigestion or heartburn is 75mg to 300mg a day. stomach ulcers and inflammation of the food pipe is 300mg to 600mg a day. Zollinger-Ellison syndrome is 450mg to 6 grams a day.

What drug class is ranitidine?

Ranitidine (also known by its brand name, Zantac, which is sold by the drug company Sanofi) is available both over the counter (OTC) and by prescription. It belongs to the class of drugs known as H2 (or histamine-2) blockers. OTC ranitidine is commonly used to relieve and prevent heartburn.

Is all ranitidine being recalled?

The FDA has requested all ranitidine (Zantac) products be pulled from the market immediately, according to a statement. The recall includes all prescription and over-the-counter ranitidine drugs as ongoing investigations uncovered levels of N-Nitrosodimethylamine (NDMA), a probable human carcinogen, increase over time.

Which brands of ranitidine have been recalled?

Sanofi issues a recall for over-the-counter brand-name Zantac 150, 150 Cool Mint and Zantac 75. This is the first brand-name recall. The FDA releases results of its NDMA testing.

Which is safer ranitidine or omeprazole?

There was no significant difference between the 10- and 20-mg doses of omeprazole (P = 0.06). Conclusions: Maintenance treatment with omeprazole (20 or 10 mg once daily) is superior to ranitidine (150 mg twice daily) in keeping patients with erosive reflux esophagitis in remission over a 12-month period.

What are the best things to drink when you have acid reflux?

What to Drink for Acid RefluxHerbal tea.Low-fat milk.Plant-based milk.Fruit juice.Smoothies.Water.Coconut water.Drinks to avoid.More items…•

Is it safe to take ranitidine?

Ranitidine is used for long-term or short-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: You may still have stomach pain caused by high amounts of acid in your stomach. This may make your condition worse.

Should I stop taking ranitidine?

What should we do? The F.D.A. has said it is not telling people to stop taking Zantac, but recommended that patients who take prescription forms of the drug and want to switch should talk to their doctor about alternatives.

What is a good substitute for ranitidine?

Proton Pump Inhibitor Zantac AlternativesEsomeprazole (brand name Nexium)Lansoprazole (brand name Prevacid)Omeprazole (brand name Prilosec)

What is the best prescription medication for acid reflux?

These include esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (Aciphex) and dexlansoprazole (Dexilant). Although generally well-tolerated, these medications might cause diarrhea, headache, nausea and vitamin B-12 deficiency.

Will ranitidine be back on the market?

Based on these findings, FDA has determined that many currently marketed ranitidine products could expose consumers to unacceptable health risks. All ranitidine products, including the oral liquid/syrup, will be withdrawn by their manufacturers and will not be available on the U.S. market.

What is the safest acid reflux medicine?

At this point, if you are concerned about taking Zantac there are alternative medications that are perfectly acceptable. Pepcid and Tagamet are both over the counter histamine blockers that can be used in place of Zantac.

What are the long term side effects of ranitidine?

The long-term side effects of Zantac are many….These include:Anemia and other concerns about blood cells.Liver function and possible liver damage.Cardiovascular concerns including a heart rate that is too slow, too fast, or irregular.Vertigo.Meningitis and other brain-related complications.Dystonia.

Is nizatidine still available?

The Axid brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

When should you take ranitidine?

Ranitidine can be taken with or without food. To prevent heartburn and acid indigestion, take ranitidine 30-60 minutes before eating food or drinking beverages that can cause indigestion. Do not take more than 2 tablets in 24 hours unless directed by your doctor. Follow all directions on the product package.