Question: What Medications Interact With Clopidogrel?

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST..

Can I drink coffee with clopidogrel?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

How long should I stay on clopidogrel?

Current guidelines say to take Plavix and aspirin every day for a month after getting a bare-metal stent and daily for at least a year after getting a drug-coated stent to prevent blood clots from forming inside a stent. Called late stent thrombosis, such clots can cause a heart attack or cardiac arrest.

What should you not take with clopidogrel?

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you’re taking clopidogrel, unless a doctor has said it’s OK. They increase the chance of bleeding. You can take paracetamol together with clopidogrel.

What drugs interact with clopidogrel?

Serious InteractionsSELECTED PLATELET AGGREGATION INHIBITORS/NSAIDS.CLOPIDOGREL/ESOMEPRAZOLE; OMEPRAZOLE; CIMETIDINE.CLOPIDOGREL/FLUCONAZOLE; KETOCONAZOLE; VORICONAZOLE.CLOPIDOGREL/ETRAVIRINE.CLOPIDOGREL/FELBAMATE.CLOPIDOGREL/TICLOPIDINE.CLOPIDOGREL/FLUOXETINE; FLUVOXAMINE.More items…

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

How do you know if clopidogrel is working?

You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working. However, if bleeding is excessive, prolonged, or you notice blood in your urine or stool, seek urgent medical advice.

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

What anti inflammatory can I take with clopidogrel?

The combination of clopidogrel with nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Aleve), diclofenac (Voltaren), etodolac (Lodine), nabumetone (Relafen), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis; Oruvail), …

What is the best time of day to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

What antacids can be taken with clopidogrel?

– Patients who use clopidogrel and need a medication to reduce stomach acid can use antacids and most H2 blockers such as Zantac (ranitidine), Pepcid (famotidine), Axid (nizatidine), but not Tagamet and Tagamet HB (cimetidine).

Can I take anti inflammatories while on blood thinners?

In general, you should avoid ibuprofen—which is sold as Advil, Motrin, and generics—while taking warfarin, because taking them together may further increase your risk of bleeding. Ibuprofen and naproxen (Aleve, Naprosyn, generics) belong to the class of drugs known as nonsteroidal anti-inflammatory drugs, or NSAIDs.